A palladium–catalyzed ring-opening reaction of 2H-azirines with hydrazones has been developed. This protocol provides an alternative route for the construction of various polysubstituted pyrazoles with a wide substrate scope. Moreover, a plausible mechanism is proposed for this reaction, which should further enrich the chemical conversion of 2H-azirines.

中文翻译：

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2H-氮杂环与腙开环反应钯催化合成多取代吡唑

已开发出钯催化的 2H-氮丙啶与腙的开环反应。该协议为构建具有广泛底物范围的各种多取代吡唑提供了一种替代途径。此外，该反应提出了一个合理的机制，这将进一步丰富 2H-氮杂环化合物的化学转化。