The synthesis of fluorinated octahydro-2H-chromene was carried out using the Prins reaction between the monoterpenoid (–)-isopulegol and carbonyl compounds in the presence of the BF₃·Et₂O–H₂O system, which acts as both an acid catalyst and a fluorine source. The use of the readily available and easy-to-use BF₃·Et₂O reagent makes this method of obtaining fluorine derivatives simple and practical.

中文翻译：

---

BF 3·Et 2 O–H 2 O催化体系合成氟化八氢-2 H-Chromenes

氟化八氢-2 H-色烯的合成是通过在BF ₃ ·Et ₂ O–H ₂ O系统的存在下单萜类（–）-异胡薄荷醇与羰基化合物之间的Prins反应进行的。酸催化剂和氟源。使用易于获得且易于使用的BF ₃ ·Et ₂ O试剂，使得该获得氟衍生物的方法简单而实用。