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Development of Technology and Equipment for Enisamium Iodide Drying
Pharmaceutical Chemistry Journal ( IF 0.9 ) Pub Date : 2020-08-01 , DOI: 10.1007/s11094-020-02233-8
M. S. Vasilishin , Yu. A. Kryukov , A. G. Karpov , O. S. Ivanov , D. B. Ivanova , S. V. Sysolyatin , A. V. Balakhnina

A methodological approach to selecting the optimal drying method for enisamium iodide, an antiviral agent with a broad spectrum of pharmacological activities, is considered. A vacuum drying method in an apparatus with a tape mixing device is proposed and verified based on studies of the main properties of the product. An industrial setup prototype and design features of the apparatus are described. The basic technological regimes of enisamium iodide drying ensuring the product quality are established. The kinetic drying and heating curves of the product, including those in the optimal regime, are presented. Test results were used to determine the specific technical parameters of the setup operation.

中文翻译:

碘化铵干燥工艺与设备的研制

考虑了一种方法学方法来选择碘化艾尼萨姆(一种具有广谱药理活性的抗病毒剂)的最佳干燥方法。在对产品主要性能的研究的基础上,提出并验证了一种带有带混合装置的设备中的真空干燥方法。描述了该设备的工业设置原型和设计特征。建立了确保产品质量的碘化铵干燥的基本技术制度。展示了产品的动态干燥和加热曲线,包括处于最佳状态的曲线。测试结果用于确定设置操作的具体技术参数。
更新日期:2020-08-01
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