This study aimed to determine the influence of intermittent hypoxia and the days required for a worker to be acclimatized in high-altitude countries. We conducted an experimental study. Ten nonsmoking male students were randomly recruited from King Saud University. Fourteen days of exposure to intermittent normobaric hypoxia (15%) was the independent variable. Heart rate (HR), respiratory frequency (RF), minute ventilation (VE), respiratory exchange ratio (RER), tidal volume (VT), oxygen uptake (VO2),VO2/kg, VO2/HR, VE/VO2, and VE/VCO2 were the dependent variables. Our results showed that 12 days of exposure to intermittent hypoxia were sufficient for workers to acclimatize to hypoxia based on their respiratory responses (i.e., HR, RF, VE). This type of acclimatization session is very important for workers who are suddenly required to work in such an environment, because prolonged exposure to high altitude without acclimatization leads to cell death due to a lack of oxygen, and this, in turn, puts workers’ lives at risk.

中文翻译：

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确定工人适应缺氧所需的时间

本研究旨在确定间歇性缺氧的影响以及工人在高海拔国家适应环境所需的天数。我们进行了一项实验研究。从沙特国王大学随机招募了 10 名不吸烟的男学生。14 天暴露于间歇性常压缺氧 (15%) 是自变量。心率 (HR)、呼吸频率 (RF)、分钟通气量 (VE)、呼吸交换比 (RER)、潮气量 (VT)、摄氧量 (VO2)、VO2/kg、VO2/HR、VE/VO2 和VE/VCO2 是因变量。我们的结果表明，暴露于间歇性缺氧 12 天足以让工人根据他们的呼吸反应（即 HR、RF、VE）适应缺氧。