Microcavity array supported lipid bilayer models of ganglioside - influenza hemagglutinin1 binding.,Chemical Communications

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Microcavity array supported lipid bilayer models of ganglioside - influenza hemagglutinin1 binding.
Chemical Communications ( IF 4.3 ) Pub Date : 2020-08-07 , DOI: 10.1039/d0cc04276e
Guilherme B Berselli ₁ , Nirod Kumar Sarangi ₁ , Aurélien V Gimenez ₁ , Paul V Murphy ₂ , Tia E Keyes ₁

Affiliation

The binding of influenza receptor (HA₁) to membranes containing different glycosphingolipid receptors was investigated at Microcavity Supported Lipid Bilayers (MSLBs). We observed that HA₁ preferentially binds to GD1a but the diffusion coefficient of the associated complex at lipid bilayer is approximately double that of the complexes formed by HA₁ GM1 or GM3.

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