Microfluidic chips have become attractive devices with enormous potential for a wide range of applications. The optimal performances of microfluidic platforms cannot be achieved using a single fabrication technique. The method of obtaining the dominant characteristic of a microfluidic chip is to combine the best qualities of different technological processes and materials. In this paper, we propose a novel, cost-effective, hybrid microfluidic chip manufacturing technologies that combine 3D printing process and xurographic technique. The standard Y-mixer was 3D printed using thermoplastic polymers, while the enclosure of the channel was achieved using the PVC lamination foils. The influence of the fabrication parameters, materials and bonding layers on the channel dimensions, performances and durability in the process of chip realization have been analysed and tested. Optimized parameters have been established for 3D fabrication process. The potential application in biomedicine and material science has been demonstrated on the example with nickel-titanium (NiTi) orthodontic archwire.

微流体芯片已成为具有广泛应用潜力的有吸引力的设备。微流体平台的最佳性能无法使用单一制造技术来实现。获得微流控芯片的主要特性的方法是将不同工艺和材料的最佳质量结合起来。在本文中，我们提出了一种新颖的，具有成本效益的混合微流控芯片制造技术，该技术将3D打印过程和X射线照相技术相结合。标准Y型混合器使用热塑性聚合物3D打印，而通道的封闭使用PVC层压箔实现。制造参数，材料和粘结层对通道尺寸的影响，对芯片实现过程中的性能和耐久性进行了分析和测试。已经为3D制造过程建立了优化参数。镍钛（NiTi）正畸弓丝的实例已证明了其在生物医学和材料科学中的潜在应用。