当前位置: X-MOL 学术Nanotechnol. Russia › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Facile Synthesis of Ultrasmall, Highly Stable, and Biocompatible Gold Nanoparticles Stabilized with Lipoic Acid: Cytotoxicity and Structural Characterization
Nanotechnologies in Russia Pub Date : 2020-07-28 , DOI: 10.1134/s199507801906003x
Delfino Cornejo-Monroy , Betania Sánchez-Santamaria , Erwin Adán Martínez-Gómez , Imelda Olivas-Armendáriz , Alfredo Villanueva-Montellano , José Saúl Arias-Cerón , Victor M. Castaño

Abstract

Using the colloidal method, and lipoic acid as a stabilizer, ultrasmall gold nanoparticles with an average size of 2.5 nm were synthesized. They are highly stable, have COOH functional groups, at concentrations lower than 100 μg/mL are non-cytotoxic, and the synthesis route is simple and economical. UV–Vis, FT-IR, Raman, and TEM spectroscopy were used to analyze their stability, composition and morphology. Furthermore, the cytotoxicity of the gold nanoparticles was evaluated by MTT assay.


中文翻译:

硫辛酸稳定的超小,高度稳定和生物相容性金纳米粒子的简便合成:细胞毒性和结构表征。

摘要

使用胶体法,以硫辛酸为稳定剂,合成了平均粒径为2.5 nm的超小金纳米粒子。它们高度稳定,具有COOH官能团,浓度低于100μg/ mL时无细胞毒性,并且合成路线简单且经济。紫外-可见,FT-IR,拉曼和TEM光谱分析了它们的稳定性,组成和形态。此外,通过MTT测定法评价了金纳米颗粒的细胞毒性。
更新日期:2020-07-28
down
wechat
bug