Abstract—

Using the colloidal method, and lipoic acid as a stabilizer, ultrasmall gold nanoparticles with an average size of 2.5 nm were synthesized. They are highly stable, have COOH functional groups, at concentrations lower than 100 μg/mL are non-cytotoxic, and the synthesis route is simple and economical. UV–Vis, FT-IR, Raman, and TEM spectroscopy were used to analyze their stability, composition and morphology. Furthermore, the cytotoxicity of the gold nanoparticles was evaluated by MTT assay.

中文翻译：

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硫辛酸稳定的超小，高度稳定和生物相容性金纳米粒子的简便合成：细胞毒性和结构表征。

摘要—

使用胶体法，以硫辛酸为稳定剂，合成了平均粒径为2.5 nm的超小金纳米粒子。它们高度稳定，具有COOH官能团，浓度低于100μg/ mL时无细胞毒性，并且合成路线简单且经济。紫外-可见，FT-IR，拉曼和TEM光谱分析了它们的稳定性，组成和形态。此外，通过MTT测定法评价了金纳米颗粒的细胞毒性。