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Sp(l)icing up PepR signalling.
Nature Plants ( IF 15.8 ) Pub Date : 2020-07-20 , DOI: 10.1038/s41477-020-0708-1
Lennart Wirthmueller 1 , Tina Romeis 1
Affiliation  

Alternative splicing provides a fundamental and ubiquitous mechanism of gene regulation. Stimuli-induced retention of introns introduces novel proteoforms with altered signalling output: full-length CPK28 blocks immune signalling, while a truncated variant, lacking calcium responsiveness, promotes it.

中文翻译:

Sp(l)提示PepR信号。

选择性剪接提供了基因调控的基本和普遍机制。刺激诱导的内含子保留引入了具有改变的信号输出的新型蛋白形式:全长CPK28阻断了免疫信号传导,而缺乏钙反应性的截短变体促进了这种信号传导。
更新日期:2020-07-20
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