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Sp(l)icing up PepR signalling

Nature Plants volume 6, pages 912–913 (2020)Cite this article

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Alternative splicing provides a fundamental and ubiquitous mechanism of gene regulation. Stimuli-induced retention of introns introduces novel proteoforms with altered signalling output: full-length CPK28 blocks immune signalling, while a truncated variant, lacking calcium responsiveness, promotes it.

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Fig. 1: PepR-induced alternative splicing overrides post-translational modification (PTM)-controlled immune suppression to allow response amplification.

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Authors and Affiliations

  1. Department of Biochemistry of Plant Interactions, Institute of Plant Biochemistry (IPB), Halle (Saale), Germany

    Lennart Wirthmueller & Tina Romeis

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  1. Lennart Wirthmueller
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  2. Tina Romeis
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Correspondence to Lennart Wirthmueller or Tina Romeis.

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Wirthmueller, L., Romeis, T. Sp(l)icing up PepR signalling. Nat. Plants 6, 912–913 (2020). https://doi.org/10.1038/s41477-020-0708-1

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