A newly designed Amoeba faced photonic crystal fiber (A-PCF) is introduced for the first time in the fields of fiber for biosensing and particularly to detect cancerous cells for instances- blood cancer (Jurkat), cervical cancer (HeLa), adrenal glands cancer (PC12), breast cancer (MDA-MB-231, MCF-7) and skin cancer (Basal), etc. In fact, proposed PCF is fabricated after the simulation studies and the application for sensing is numerically investigated by the discrete finite element method (D-FEM) by the simulation of about 22,105 mesh elements. Moreover, the numerical analysis is justified by full vector simulation software COMSOL V-5.1 and considering the refractive indices from it. Also, different sections are considered for the analyte cavity to analyze the performance variations. Nonetheless, Few parameters like birefringence, coupling length, power fraction, transmittance, wavelength sensitivity, and transmittance sensitivity are evaluated through the refractive indices of the cancerous cell compared to its normal cell and the most optimum profile are respectively to 3.5 × 10⁻³, 900 μm, 0.891, -178 dB, 18115.94 nm/RIU and 6071.42 dB/RIU. Nonetheless, the fabrication of the PCF can be achieved by using current fabrication technology such as stack-and-draw, sol-gel or the extrusion and drilling techniques that help to overcome all the primary difficulties of the proposed PCF.

一种新设计的面向变形虫的光子晶体光纤（A-PCF）首次用于生物传感光纤领域，尤其是用于检测癌细胞的血液-癌症（Jurkat），宫颈癌（HeLa），肾上腺癌（PC12），乳腺癌（MDA-MB-231，MCF-7）和皮肤癌（基础）等。实际上，拟议的PCF是在模拟研究之后制成的，并且通过离散有限元对传感应用进行了数值研究方法（D-FEM）通过模拟约22,105个网格元素。此外，通过全矢量仿真软件COMSOL V-5.1并考虑其折射率可以证明数值分析的正确性。另外，考虑了分析物腔的不同部分以分析性能变化。但是，很少有参数，例如双折射，耦合长度，^-3，900微米，0.891，-178分贝，18115.94纳米/ RIU和6071.42分贝/ RIU。尽管如此，仍可以通过使用当前的制造技术（例如叠放，溶胶凝胶或挤压和钻孔技术）来完成PCF的制造，这些技术可帮助克服所提出的PCF的所有主要困难。