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A Review on the Prevalence of Toxoplasma gondii in Humans and Animals Reported in Malaysia from 2008-2018.
International Journal of Environmental Research and Public Health ( IF 4.614 ) Pub Date : 2020-07-03 , DOI: 10.3390/ijerph17134809
Mohammed Nasiru Wana 1, 2 , Mohamad Aris Mohd Moklas 3 , Malaika Watanabe 4 , Norshariza Nordin 5 , Ngah Zasmy Unyah 1 , Sharif Alhassan Abdullahi 1, 6 , Ashraf Ahmad Issa Alapid 1, 7 , Tijjani Mustapha 1, 8 , Rusliza Basir 3 , Roslaini Abd Majid 9
Affiliation  

Toxoplasmosis is a disease caused by the protozoan parasite Toxoplasma gondii (T. gondii). Human toxoplasmosis seroprevalence in Malaysia has increased since it was first reported in 1973 as shown in previous reviews of 1991 and 2007. However, over a decade since the last review, comprehensive data on toxoplasmosis in Malaysia is lacking. This work aimed at reviewing articles on toxoplasmosis research in Malaysia in order to identify the research gaps, create public awareness, and efforts made so far and proffer management options on the disease. The present review examines the available published research articles from 2008 to 2018 related to toxoplasmosis research conducted in Malaysia. The articles reviewed were retrieved from nine credible databases such as Web of Science, Google Scholar, ScienceDirect, PubMed, Scopus, Springer, Wiley online library, Ovid, and Cochrane using the keywords; Malaysia, toxoplasmosis, Toxoplasma gondii, toxoplasma encephalitis, seroprevalence, human immunodeficiency virus (HIV) patients, pregnant women, genotype strain, anti-toxoplasma antibodies, felines, and vaccine. The data highlighted seropositive cases from healthy community members in Pangkor Island (59.7%) and among migrant workers (57.4%) at alarming rates, as well as 42.5% in pregnant women. Data on animal seroprevalence were limited and there was no information on cats as the definitive host. Genetic characterization of Toxoplasma gondii from HIV patients; pregnant women, and domestic cats is lacking. This present review on toxoplasmosis is beneficial to researchers, health workers, animal health professionals, and policymakers. Therefore, attention is required to educate and enlighten health workers and the general public about the risk factors associated with T. gondii infection in Malaysia.

中文翻译:

2008-2018年马来西亚报道的弓形虫在人和动物中的流行情况回顾。

弓形虫病是由原生动物寄生虫弓形虫T. gondii)引起的)。自1973年首次报道以来,马来西亚的人类弓形虫血清阳性率有所增加,如1991年和2007年的先前评论所示。但是,自上次审查以来的十多年中,缺乏关于马来西亚弓形虫病的全面数据。这项工作旨在审查有关马来西亚弓形虫病研究的文章,以找出研究空白,提高公众认识,并做出了迄今为止的努力并提供了对该疾病的管理选择。本综述审查了2008年至2018年有关在马来西亚进行的弓形虫病研究的可用已发表研究文章。使用关键词从9个可靠的数据库(如Web of Science,Google Scholar,ScienceDirect,PubMed,Scopus,Springer,Wiley在线图书馆,Ovid和Cochrane)检索检索到的文章;马来西亚,弓形虫病,弓形虫,弓形虫脑炎,血清流行,人类免疫缺陷病毒(HIV)患者,孕妇,基因型毒株,抗弓形虫抗体,猫科动物和疫苗。数据突出显示了邦咯岛健康社区成员的血清反应阳性病例(59.7%)和民工血清反应阳性病例(57.4%)的发生率令人震惊,孕妇为42.5%。关于动物血清阳性率的数据是有限的,没有关于猫作为确定宿主的信息。弓形虫的遗传特征来自艾滋病毒患者;孕妇和家猫不足。目前关于弓形虫病的评论对研究人员,卫生工作者,动物卫生专业人员和决策者都是有益的。因此,需要注意教育和启发卫生工作者和公众,了解马来西亚与弓形虫感染相关的危险因素。
更新日期:2020-07-03
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