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The “authentic subjective experience” of memory in Alzheimer’s disease
Translational Neuroscience ( IF 1.8 ) Pub Date : 2020-06-03 , DOI: 10.1515/tnsci-2020-0123
Mohamad El Haj 1, 2, 3 , Ahmed A. Moustafa 4, 5 , Jean Roche 6 , Florence Pasquier 7 , Dimitrios Kapogiannis 8 , Karim Gallouj 2 , Pascal Antoine 9
Affiliation  

Most research has mainly focused on the decline of the subjective experience in Alzheimer’s disease (AD). However, few attempts have been made to evaluate whether subjective experience may be maintained in AD. In this narrative review, we attempt to provide a positive view, according to which patients with AD can enjoy, to some extent, subjective experience during memory retrieval. Memory and expression difficulties (e.g., aphasia) limit the ability of patients with AD to describe their memories, resulting in a little specificity of reported memories. However, according to the “authentic subjective experience” view, we propose in this study that the ability to mentally relive these memories could be preserved in the patients. By proposing the authentic subjective experience view, we attempt to provide an alternative view to the general consideration that the patients suffer a diminished subjective experience. This view can contribute to a larger clinical framework that gives a positive meaning to the subjective experience of patients with AD. Furthermore, several clinical and empirical implications can be drawn from the authentic subjective experience view, including the possibility to evaluate behavioral correlates of the subjective experience in AD.

中文翻译:

阿尔茨海默氏病记忆的“真实主观体验”

大多数研究主要集中于阿尔茨海默氏病(AD)的主观经验下降。但是,很少有人尝试评估是否可以在AD中保持主观经验。在这篇叙述性综述中,我们试图提供一种积极的观点,据此,AD患者可以在一定程度上享受记忆检索期间的主观体验。记忆和表达困难(例如失语症)限制了AD患者描述其记忆的能力,从而导致所报告记忆的特异性较低。然而,根据“真实的主观经验”的观点,我们在这项研究中建议可以在患者中保留精神记忆这些记忆的能力。通过提出真实的主观体验视图,我们试图为患者遭受主观经验减少的一般考虑提供另一种观点。这种观点可以有助于建立更大的临床框架,从而为AD患者的主观体验提供积极的意义。此外,可以从真实的主观经验观点得出一些临床和经验意义,包括评估AD中主观经验的行为相关性的可能性。
更新日期:2020-06-30
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