Abstract—The receptor specificity for the A/rook/Chany/32/2015 (H5N1), A/common gull/Saratov/1676/2018 (H5N6), and A/chicken/PrimorskyKrai/03/2018 (Н9N2) strains of avian influenza virus has been studied. Using the method of surface plasmon resonance for the selected strains we obtained the values ​​of the equilibrium dissociation constants with analogues of receptors such as α2-3 and α2-6. It was found that for strains A/rook/Chany/32/2015 (H5N1) and A/common gull/Saratov/1676/2018 (H5N6), a binding with the human type of receptor (α2-6) is determined, in contrast to the strain A/chicken/PrimorskyKrai/03/2018 (H9N2), which is specific only for avian type receptors (α2-3).

中文翻译：

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用表面等离子体共振法分析甲型流感病毒株的受体特异性

摘要——A/rook/Chany/32/2015 (H5N1)、A/common gull/Saratov/1676/2018 (H5N6) 和 A/chicken/PrimorskyKrai/03/2018 (Н9N2) 禽类毒株的受体特异性流感病毒进行了研究。使用选定菌株的表面等离子体共振方法，我们获得了与受体类似物（如 α2-3 和 α2-6）的平衡解离常数值。发现对于菌株 A/rook/Chany/32/2015 (H5N1) 和 A/common gull/Saratov/1676/2018 (H5N6)，确定了与人类类型受体 (α2-6) 的结合，在与 A/chicken/PrimorskyKrai/03/2018 (H9N2) 菌株形成对比，后者仅针对禽类受体 (α2-3)。