In the evolving field of adaptive MR guided radiotherapy, the need for dedicated procedures for acceptance and quality assurance is increasing. Research has been devoted to MR compatible dosimeters and phantoms, but to date no end-to-end test has been presented that covers an MRgRT workflow. Such an end-to-end test should comprise each step of the workflow and include all associated uncertainties. The purpose of this study was to investigate the usability of an anthropomorphic deformable and multimodal pelvis (ADAM-pelvis) phantom in combination with film dosimetry for end-to-end testing of an MRgRT adaptive workflow. The ADAM-pelvis phantom included surrogates for muscle tissue, adipose and bone, as well as deformable silicone organs mimicking a prostate patient. At the interfaces of the critical structures (bladder and rectum), small pieces of GafChromic EBT3 films were placed to measure delivered dose. Pre-treatment MR imaging of the phantom was used to delineate the p...

中文翻译：

---

MR引导的在线自适应放射治疗的端到端测试

在自适应MR引导的放射治疗的不断发展的领域中，对用于接受和质量保证的专用程序的需求正在增加。已经针对MR兼容剂量计和体模进行了研究，但是迄今为止，还没有提出涵盖MRgRT工作流程的端到端测试。这样的端到端测试应包括工作流的每个步骤，并包括所有相关的不确定性。这项研究的目的是调查拟人化可变形和多模式骨盆（ADAM-骨盆）幻影结合胶片剂量法用于MRgRT自适应工作流程的端到端测试的可用性。ADAM-骨盆模型包括用于肌肉组织，脂肪和骨骼的替代物，以及可模仿前列腺患者的可变形硅酮器官。在关键结构（膀胱和直肠）的界面处，放置小块GafChromic EBT3膜以测量递送剂量。幻影的预处理MR成像用于描绘幻影。