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Unraveling proteasome engagement.
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2020-06-15 , DOI: 10.1038/s41589-020-0573-2
Cameron G Roberts 1 , Jonathan N Pruneda 1
Affiliation  

A new study reveals that, in addition to its longstanding role in recruiting proteins to the proteasome, ubiquitination can also induce a structural destabilization that allows the target protein to be efficiently unraveled for degradation.

中文翻译:

打破蛋白酶的参与。

一项新的研究表明,泛素化除了在将蛋白质募集到蛋白酶体中的长期作用外,还可以诱导结构失稳,从而使目标蛋白质得以有效分解。
更新日期:2020-06-15
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