Objective. To explore the impact of different electrical stimulation profiles in human recipients of the Geneva-Maastricht vestibular implant prototypes. Approach. Four implanted patients were recruited for this study. We investigated the relative efficacy of systematic variations of the electrical stimulus profile (phase duration, pulse rate, baseline level, modulation depth) in evoking vestibulo-ocular (eVOR) and perceptual responses. Main results. Shorter phase durations and, to a lesser extent, slower pulse rates allowed maximizing the electrical dynamic range available for eliciting a wider range of intensities of vestibular percepts. When either the phase duration or the pulse rate was held constant, current modulation depth was the factor that had the most significant impact on peak velocity of the eVOR. Significance. Our results identified important parametric variations that influence the measured responses. Furthermore, we observed that not...

中文翻译：

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刺激曲线的系统变化对人类前庭植入原型引起的反应的影响。

客观的。探索不同电刺激模式对日内瓦-马斯特里赫特前庭植入原型的人类接受者的影响。方法。这项研究招募了四名植入患者。我们研究了电刺激曲线（相持续时间、脉冲速率、基线水平、调制深度）的系统变化在引起前庭眼（eVOR）和知觉反应中的相对功效。主要结果。较短的相位持续时间以及在较小程度上较慢的脉冲速率允许最大化可用于引发更广泛的前庭感知强度的电动态范围。当相位持续时间或脉冲速率保持恒定时，电流调制深度是对 eVOR 峰值速度影响最显着的因素。意义。我们的结果确定了影响测量响应的重要参数变化。此外，我们观察到不...