Two methods based on direct immersion single-drop microextraction (DI-SDME) and continuous-flow microextraction (CFME) were developed. Both methods were used for the determination of manganese by graphite furnace atomic absorption spectrometry. The reagent 1-(2-pyridylazo)-2-naphthol (PAN) was used as a complexing agent and 1-butyl-3-methylimidazolium hexafluorophosphate [C₄MIM][PF₆] as an extraction solvent. The extraction efficiencies were compared so that some variables, such as the volume of solvent, time of extraction, stirring speed, and flow rate, were optimized using the univariate method. The limits of detection were 3.9 and 7.9 ng L⁻¹ for DI-SDME and CFME methods, respectively. The enrichment factor for DI-SDME was 18 and for CFME was 15. The accuracy of the method was assessed by analyzing the certified reference material of mussel tissue (SEM 2976), and recovery tests ranged from 92 to 112%. The two categories of LPME are presented as excellent alternatives for the determination of manganese in real samples of tonic drinks and seafood, showing benefits such as low consumption of reagents, ease of operation, and low cost. The DI-SDME-based method is superior to the CFME method if practical aspects are considered, especially for two advantages: less sample volume required and less time to reach equilibrium.

开发了两种基于直接浸入单滴微萃取（DI-SDME）和连续流微萃取（CFME）的方法。两种方法都用于石墨炉原子吸收光谱法测定锰。将试剂1-（2-吡啶基偶氮）-2-萘酚（PAN）用作络合剂，并将1-丁基-3-甲基咪唑六氟磷酸盐[C ₄ MIM] [PF ₆ ]用作萃取溶剂。比较萃取效率，以便使用单变量方法优化一些变量，例如溶剂量，萃取时间，搅拌速度和流速。检测限为3.9和7.9 ng L ^-1分别用于DI-SDME和CFME方法。DI-SDME的富集系数为18，CFME的富集系数为15。该方法的准确性通过分析经过认证的贻贝组织参考材料（SEM 2976）进行评估，回收率测试范围为92％至112％。LPME的两类是测定滋补饮料和海鲜的真实样品中锰的极佳替代品，具有诸如试剂消耗低，操作简便和成本低等优点。如果考虑实际方面，则基于DI-SDME的方法要优于CFME方法，尤其是具有两个优势：所需的样品量更少，达到平衡所需的时间更少。