Abstract

The methanol extract form the leaves of Phytolacca icosandra L., afforded the unprecedented artificial triterpenoid fatty acid ester 1 derived from the new natural triterpenoid phytolaccagenic acid 3-O-myristate (1a), along with the three known triterpenoids serjanic, acinosolic and phytolaccagenic acid (2 – 4). Their structures were stablished by HR-EI-MS, 1D and 2D NMR techniques. The possible mechanistic formation of 1 is proposed, and the in vitro toxicity of all compounds was assessed using the brine shrimp lethality assay (BSLA).

Graphic Abstract

中文翻译：

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从商陆叶中分离的人工三萜脂肪酸酯。

 抽象的

商陆 (Phytolacca icosandra L.) 叶子的甲醇提取物，提供了前所未有的人工三萜脂肪酸酯1 ，该酯源自新的天然三萜 phytolaccagenic Acid 3- O -myristate ( 1a )，以及三种已知的三萜化合物 serjanic、acinosolic 和 phytolaccagenic Acid （ 2-4 ） 。通过HR-EI-MS、一维和二维核磁共振技术确定了它们的结构。提出了1的可能形成机制，并使用丰年虾致死试验（BSLA）评估了所有化合物的体外毒性。

 图文摘要