The availability of clinical-relevant large animal models for research in wound healing study is limited. Although a few reports described the wound dressing fixation method using polyurethane foam in patients, no animal studies were conducted to investigate efficacy of the polyurethane foam in grafted burn wounds. In the present study, we report a simple fixation method of grafted burned skin using polyurethane foam dressing (Allevyn Non-Adhesive, smith & nephew, UK) in a clinically relevant ovine grafted burn wound model. The dressing was removed at postoperative day 7 after skin graft. The grafted skin was completely engrafted without any complications. This method was safe and easy to perform and associated with good engraftment without any complications. We believe that the polyurethane foam fixation method may be successfully used in clinical practice as well as in preclinical studies for grafted burn wound repair and regeneration research.

与临床相关的大型动物模型在伤口愈合研究中的可用性有限。尽管一些报道描述了在患者中使用聚氨酯泡沫进行伤口包扎固定的方法，但并未进行动物研究来研究聚氨酯泡沫在烧伤创面中的功效。在本研究中，我们报告了在临床相关的羊皮移植烧伤创面模型中使用聚氨酯泡沫敷料（英国Allevyn Non-Adhesive，Smith＆Nephew，英国）的一种简单的植皮烧伤固定方法。皮肤移植术后第7天取下敷料。移植的皮肤完全植入，没有任何并发​​症。该方法安全且易于实施，并且与良好的植入相关，没有任何并发​​症。