Abstract

Aryl acetylenes bearing electron-withdrawing groups have been found that can add to azulenes and yield 1,2-substituted heptalenes. Theoretical studies of the reaction mechanism helped to design the candidate molecules that have then been tested in the synthetic work. New heptalenes are obtained by reacting methyl (4-nitrophenyl)propiolate with either 4,6,8-trimethylazulene or guaiazulene, as well as 3-(4-nitrophenyl)-2-propyn-1-ol with guaiazulene. This opens a new synthetic route to 1-aryl-substituted heptalenes.

中文翻译：

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通过将芳基乙炔加到Azulenes中来合成庚烯

摘要

已经发现带有吸电子基团的芳基乙炔可以加成天青烯并产生1，2-取代的庚烷。反应机理的理论研究有助于设计候选分子，然后在合成工作中对其进行测试。通过使（4-硝基苯基）丙酸甲酯与4,6,8-三甲基methyl烯或愈创木酚以及3-（4-硝基苯基）-2-丙炔-1-醇与愈创木烯反应，得到新的庚烯。这为1-芳基取代的庚烯开辟了一条新的合成途径。