Abstract A series of new functionalized allenoates has been synthesized, and their cytotoxic effect has been studied against the tumor cell line (HepG2 and Jurkat) and the normal origin cells (HEK293). The highest cytotoxic effect has been shown for diterpene-containing allenic compounds, which can be attributed to promising substances with potential antitumor activity.

中文翻译：

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多种功能化 2,3-烯丙酸酯的合成和细胞毒活性

摘要 合成了一系列新的功能化烯丙酸酯，并研究了它们对肿瘤细胞系（HepG2 和 Jurkat）和正常来源细胞（HEK293）的细胞毒作用。含有二萜的丙二烯化合物显示出最高的细胞毒性作用，这可归因于具有潜在抗肿瘤活性的有前途的物质。