Abstract

Objective The aim of the study was to determine the changes in biomechanical characteristics following tibial plateau levelling osteotomy (TPLO) using simulated manual tests.

Study Design Twenty-one stifles from healthy Beagle dogs that had undergone TPLO or had not (control) were first tested in the intact form, and then the cranial cruciate ligament (CrCL) was transected in each to provide four test situations: control-intact, control-CrCL-transected, TPLO-intact and TPLO-CrCL-transected. The stifles were then analysed using a robotic joint biomechanical testing system. The craniocaudal drawer, axial rotation and proximal compression tests were applied.

Results The craniocaudal displacement during the drawer test was not significantly different between the control-intact and TPLO-intact. However, the displacement was significantly greater in the TPLO-CrCL-transected than in the control-intact. In the axial rotation test, the internal–external (IE) rotation was significantly greater in the TPLO-intact than in the control-intact. Similarly, the IE rotation was significantly greater in the TPLO-CrCL-transected than in the control-CrCL-transected. In the proximal compression test, craniocaudal displacement was not significantly different among the control-intact, TPLO-intact and TPLO-CrCL-transected.

Conclusion These findings suggest that TPLO influences the tension of the collateral ligaments and might generate laxity of the tibiofemoral joint. Instability after the osteotomy might be associated with the progression of osteoarthritis.

Authors' Contributions

All authors contributed to conception of study, study design, acquisition of data and data analysis and interpretation. All authors also drafted, revised and approved the submitted manuscript.

中文翻译：

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胫骨平台平整截骨术对正常犬窒息关节不稳定性的生物力学影响：一项体外研究。

摘要

目的 本研究的目的是使用模拟手动测试确定胫骨平台平整截骨术（TPLO）后生物力学特征的变化。

研究设计 首先以完整形式测试来自经历过TPLO或未（对照）的健康Beagle犬的21个窒息，然后分别横切颅交叉韧带（CrCL），以提供四种测试情况：对照完整，对照CrCL横切，完整TPLO和TPLO-CrCL横切。然后使用机器人关节生物力学测试系统分析气钉。进行了颅尾抽屉，轴向旋转和近端压缩测试。

结果 抽屉试验期间的颅尾移位在对照完整和TPLO完整之间无显着差异。但是，TPLO-CrCL横切的位移明显大于对照完整的。在轴向旋转测试中，TPLO完整性中的内部-外部（IE）旋转显着大于对照完整性。同样，在TPLO-CrCL横切中，IE旋转明显大于在对照-CrCL横切中的IE旋转。在近端压缩测试中，在完整对照，TPLO完整和TPLO-CrCL完整之间，颅尾移位无明显差异。

结论 这些发现表明TPLO影响了副韧带的张力，并可能导致胫股关节松弛。截骨后的不稳定性可能与骨关节炎的进展有关。

作者的贡献

所有作者都为研究概念，研究设计，数据获取以及数据分析和解释做出了贡献。所有作者还起草，修改和批准了提交的手稿。