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Raising the ribosomal repertoire.
Nature Chemistry ( IF 19.2 ) Pub Date : 2020-05-29 , DOI: 10.1038/s41557-020-0476-6
Christopher D Reinkemeier 1, 2, 3 , Edward A Lemke 1, 2, 3
Affiliation  

Three versatile and mutually orthogonal tRNA/aminoacyl-tRNA synthetase pairs have been developed. Collectively, these pairs enable the site-specific incorporation of three different non-canonical amino acids into a protein that can still be terminated faithfully by a natural stop codon.

中文翻译:

提高了核糖体库。

已经开发了三种通用且相互正交的tRNA /氨酰基-tRNA合成酶对。总的来说,这些对使得能够将三种不同的非经典氨基酸位点特异性掺入蛋白质中,而该蛋白质仍可以如实地被天然终止密码子终止。
更新日期:2020-05-29
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