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Letting off electrons to cope with metabolic stress.
Nature Metabolism ( IF 20.8 ) Pub Date : 2020-05-27 , DOI: 10.1038/s42255-020-0207-8
Collin D Heer 1, 2 , Charles Brenner 2
Affiliation  

Whereas textbooks depict metabolism in perfect homeostasis, disturbances occur in real life. One particularly relevant disturbance, caused by excess food and alcohol consumption and exacerbated by genetics, is reductive stress. New work by Goodman et al. identifies a biomarker of reductive stress and uses a gene therapy solution in mice. This work suggests how exercise and an accessible nutritional technology can synergistically increase catabolism and relieve reductive stress.

中文翻译:

释放电子以应对代谢压力。

教科书描述了新陈代谢中的最佳稳态,而现实生活中却出现了干扰。由减少的食物和酒精消耗引起的并且由于遗传学而加剧的一种特别相关的干扰是减轻压力。Goodman等人的新作品。可以识别减轻压力的生物标记,并在小鼠中使用基因治疗解决方案。这项工作表明运动和可获取的营养技术如何协同增效分解代谢和减轻压力。
更新日期:2020-05-27
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