Biogenic amines (BA) are chemical compounds formed in foods that contain protein, allowing the foods to undergo a bacterial degradation process. Biogenic amines are labeled as toxic food because its consumption exceeding the FDA regulation (50 mg/kg) can be harmful to humans. Some countries also have regulations that prohibit the consumption of biogenic amines in high concentrations, especially histamine. The chromatography methods generally applied by researchers are liquid chromatography (LC) and gas chromatography (GC), where the use of a derivatization reagent is necessary to increase their sensitivity. This review is based on past and present studies about biogenic amine detection related to food samples. The rationale of this study is also to provide data on the comparison of the analytical approaches between LC and GC methods. Furthermore, the various approaches of biogenic amine determination and the most applied analytical methods have been reviewed.

中文翻译：

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食品和饮料中生物胺检测中色谱应用中衍生试剂的重要性。

生物胺（BA）是在含有蛋白质的食品中形成的化学化合物，可让食品经历细菌降解过程。生物胺被标记为有毒食品，因为其消费量超过FDA规定（50 mg / kg）可能对人体有害。一些国家也有法规禁止食用高浓度的生物胺，尤其是组胺。研究人员通常采用的色谱方法是液相色谱（LC）和气相色谱（GC），其中必须使用衍生化试剂以提高其灵敏度。这篇评论是基于与食品样品有关的生物胺检测的过去和现在的研究。这项研究的基本目的还在于提供有关LC和GC方法之间分析方法比较的数据。此外，