Abstract

Molecular mechanisms of the participation of proteins in reactive oxygen species (ROS) generation resulting from the singlet-oxygen effect upon laser exposure in solutions of various proteins are considered. The kinetic equations describing ROS generation are derived, and their approximate general solution is found in the analytical form. By comparison of the found kinetic dependences with experimental data, orders and rate constants of corresponding chemical reactions are determined. An analysis of the results makes it possible to consider that fundamental mechanisms of ROS formation reactions in solutions of various proteins are identical.

中文翻译：

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蛋白质水溶液中光氧作用的动力学

摘要

考虑了蛋白质参与各种蛋白质溶液中激光暴露时的单线态氧效应所导致的活性氧（ROS）生成的分子机制。推导了描述ROS生成的动力学方程，并以解析形式找到了它们的近似一般解。通过将发现的动力学依赖性与实验数据进行比较，可以确定相应化学反应的阶数和速率常数。对结果的分析可以考虑各种蛋白质溶液中ROS形成反应的基本机理是相同的。