Advancement in technology has led to the development of highly sensitive, accurate, efficient and robust analytical instrumentals, but without sample preparation, these state-of-the-art instruments are not capable of analyzing samples. Liquid-liquid extraction (LLE) was a widely used sample preparation technique, but setbacks such as long extraction periods, consumption of toxic solvents in large amounts and low efficiency led to its miniaturization, which is commonly termed liquid phase microextraction (LPME). LPME methods such as single drop microextraction, dispersive liquid-liquid microextraction and solidified floating organic drop microextraction overcome the limitations of the conventional LLE, and recent researches have focused on greener microextraction strategies based on extractants like ionic liquids and switchable polarity solvents. This review is aimed at presenting readers with a comprehensive overview of liquid phase microextraction methods, recent developments and novel approaches that are used to extract/preconcentrate endocrine disruptive compounds from food matrices for instrumental analysis.

技术的进步导致了高度灵敏，准确，高效和鲁棒的分析仪器的发展，但如果没有样品制备，这些先进的仪器就无法分析样品。液-液萃取（LLE）是一种广泛使用的样品制备技术，但由于萃取时间长，有毒溶剂的大量消耗和效率低下等挫折，导致其小型化，通常称为液相微萃取（LPME）。诸如单滴微萃取，分散液-液微萃取和固化的漂浮有机液滴微萃取等LPME方法克服了传统LLE的局限性，最近的研究集中在基于萃取剂（如离子液体和可转换极性溶剂）的绿色微萃取策略上。