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A BAD portion of glucose can be good for inflamed beta cells.
Nature Metabolism ( IF 18.9 ) Pub Date : 2020-05-11 , DOI: 10.1038/s42255-020-0198-5
Christian Frezza 1
Affiliation  

Exposure to high glucose under inflammatory conditions is detrimental to insulin-secreting beta cells in the pancreas. Fu and colleagues describe a metabolic axis that decreases production of the ‘danger molecule’ nitric oxide and improves the survival of beta cells exposed to an inflammatory milieu, thus paving the way to new interventions for diabetes.

中文翻译:

葡萄糖的 BAD 部分可能对发炎的 β 细胞有益。

在炎症条件下接触高葡萄糖对胰腺中分泌胰岛素的 β 细胞有害。Fu 及其同事描述了一种代谢轴,它减少了“危险分子”一氧化氮的产生,并提高了暴露于炎症环境的 β 细胞的存活率,从而为糖尿病的新干预措施铺平了道路。
更新日期:2020-05-11
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