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A BAD portion of glucose can be good for inflamed beta cells

Nature Metabolism volume 2, pages 383–384 (2020)Cite this article

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A Publisher Correction to this article was published on 15 June 2020

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Exposure to high glucose under inflammatory conditions is detrimental to insulin-secreting beta cells in the pancreas. Fu and colleagues describe a metabolic axis that decreases production of the ‘danger molecule’ nitric oxide and improves the survival of beta cells exposed to an inflammatory milieu, thus paving the way to new interventions for diabetes.

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Fig. 1: The metabolic axis elucidated by Fu and colleagues.

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  1. MRC Cancer Unit, University of Cambridge, Cambridge, UK

    Christian Frezza

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  1. Christian Frezza
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Correspondence to Christian Frezza.

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C.F. is a member of the scientific advisory board of Owlstone Medicals and a scientific advisor of Istesso.

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Frezza, C. A BAD portion of glucose can be good for inflamed beta cells. Nat Metab 2, 383–384 (2020). https://doi.org/10.1038/s42255-020-0198-5

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