The aim of the study is the research and identification of a Streptomyces strain as a new producer of spectinabilin, undecylprodigiosin and metacycloprodigiosin. Among 54 actinomycete isolates isolated from El-Ogbane forest soils in Algeria, only one isolate, designated V002, was selected for its ability to produce prodigiosins. The selected strain was analysed for its ability to produce three different secondary metabolites as well as their biological activities. V002 belongs to the Streptomyces genus and has significant antimicrobial and antioxidant activities. The taxonomic position of V002 by 16S rRNA sequence analysis showed a similarity of 99.93% with Streptomyces lasiicapitis DSM 103124T and 98.96% with Streptomyces spectabilis DSM 40512T. Fractionation of crude secondary metabolites produced by the strain using HPLC–MS revealed the presence of spectinabilin, undecylprodigiosin and metacycloprodigiosin, which demonstrated significant activity. Strain V002 is considered a new producer of spectinabilin, undecylprodigiosin and metacycloprodigiosin with significant antimicrobial and antioxidant activity.

中文翻译：

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森林放线菌 V002 作为壮观蛋白、十一烷基灵菌红素和元环灵菌红素新生产者的抗菌和抗氧化作用

该研究的目的是研究和鉴定作为壮观蛋白、十一烷基灵菌红素和元环灵菌红素的新生产者的链霉菌菌株。在从阿尔及利亚 El-Ogbane 森林土壤中分离出的 54 种放线菌分离物中，只有一种分离物，命名为 V002，因其产生灵菌红素的能力而被选中。分析了所选菌株产生三种不同次生代谢物的能力及其生物活性。V002 属于链霉菌属，具有显着的抗菌和抗氧化活性。通过16S rRNA序列分析，V002的分类位置与链霉菌DSM 103124T相似度为99.93%，与壮观链霉菌DSM 40512T相似度为98.96%。使用 HPLC-MS 对该菌株产生的粗次生代谢物进行分级分离，显示存在壮观蛋白、十一烷基灵菌红素和元环灵菌红素，显示出显着的活性。菌株 V002 被认为是壮观蛋白、十一烷基灵菌红素和元环灵菌红素的新生产者，具有显着的抗菌和抗氧化活性。