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Food-Derived Anticancer Peptides: A Review
International Journal of Peptide Research and Therapeutics ( IF 2.0 ) Pub Date : 2020-04-18 , DOI: 10.1007/s10989-020-10063-1
Poorva Sharma , Harjeet Kaur , Bababode Adesegun Kehinde , Navnidhi Chhikara , Deepansh Sharma , Anil Panghal

Cancer has gained appreciable attention in the category of noncommunicable health disorders as the group of proliferative diseases and metabolic syndromes of fatal consequence, globally. The conventional chemotherapeutic, radiological and associated pharmacotherapeutic advances for its cure have timelessly displayed severe aftereffects in patients. Furthermore, the underlying costs and technical requirements of these have added to their limitation recitals. Food-derived bioactive peptides have been scientifically proven as suitable alternatives for cancer management. Studies have shown that some attributes they possess such as specificity, smaller sizes, better ease of syntheses and modification, and improved penetration into cell membranes make them better alternatives to some protein isolates. Their comparative precedencies with regards to natural and efficacy with minimal side effects have offered them the recognition as proficient options in cancer therapy. This review integrates contemporary technical information about bioactive peptides from plants and animal foods and food by-products and their experimentally determined potentials as remedies for cancer. Furthermore, technical details about their isolation methodologies are offered. This article is an augmentation to technical literatures on the cancer subject and an academic exposure of the food-originated approach for its management.



中文翻译:

食品衍生的抗癌肽:综述

在全球范围内,作为非致命性疾病的增生性疾病和代谢综合症,癌症已在非传染性疾病中引起了广泛关注。用于其治愈的常规化学治疗,放射学和相关的药物治疗进展已在患者中永久显示出严重的后遗症。此外,这些的基本成本和技术要求增加了其限制陈述。食品来源的生物活性肽已被科学证明是治疗癌症的合适替代品。研究表明,它们具有某些特性,例如特异性,更小的尺寸,更易于合成和修饰以及对细胞膜的渗透性增强,使其成为某些蛋白质分离物的更好替代品。他们在天然和功效方面具有相对较小的优势,且副作用极小,这使他们被公认是癌症治疗中的精通选择。这篇综述整合了有关来自动植物食品和食品副产物的生物活性肽及其通过实验确定的潜力作为癌症疗法的当代技术信息。此外,还提供了有关其隔离方法的技术细节。本文是有关癌症主题的技术文献的补充,也是对食品起源的方法进行管理的学术见解。这篇综述整合了有关来自动植物食品和食品副产物的生物活性肽及其通过实验确定的潜力作为癌症疗法的当代技术信息。此外,还提供了有关其隔离方法的技术细节。本文是有关癌症主题的技术文献的补充,也是对食品起源的方法进行管理的学术见解。这篇综述整合了有关来自动植物食品和食品副产物的生物活性肽及其通过实验确定的潜力作为癌症疗法的当代技术信息。此外,还提供了有关其隔离方法的技术细节。本文是有关癌症主题的技术文献的补充,也是对食品起源的方法进行管理的学术见解。

更新日期:2020-04-24
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