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Food-Derived Anticancer Peptides: A Review

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Abstract

Cancer has gained appreciable attention in the category of noncommunicable health disorders as the group of proliferative diseases and metabolic syndromes of fatal consequence, globally. The conventional chemotherapeutic, radiological and associated pharmacotherapeutic advances for its cure have timelessly displayed severe aftereffects in patients. Furthermore, the underlying costs and technical requirements of these have added to their limitation recitals. Food-derived bioactive peptides have been scientifically proven as suitable alternatives for cancer management. Studies have shown that some attributes they possess such as specificity, smaller sizes, better ease of syntheses and modification, and improved penetration into cell membranes make them better alternatives to some protein isolates. Their comparative precedencies with regards to natural and efficacy with minimal side effects have offered them the recognition as proficient options in cancer therapy. This review integrates contemporary technical information about bioactive peptides from plants and animal foods and food by-products and their experimentally determined potentials as remedies for cancer. Furthermore, technical details about their isolation methodologies are offered. This article is an augmentation to technical literatures on the cancer subject and an academic exposure of the food-originated approach for its management.

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Authors and Affiliations

  1. School of Agriculture, Lovely Professional University, Phagwara, Punjab, 144 411, India

    Poorva Sharma & Harjeet Kaur

  2. Department of Biosystems and Agricultural Engineering, University of Kentucky, Lexington, KY, 40503, USA

    Bababode Adesegun Kehinde

  3. Department of Food Technology, Guru Jambheshwar University of Science and Technology, Hisar, 125001, India

    Navnidhi Chhikara

  4. Amity Institute of Microbial Technology, Amity University Rajasthan, Jaipur, 303002, India

    Deepansh Sharma

  5. Department of Processing and Food Engineering, AICRP-PHET, Chaudhary Charan Singh Haryana Agricultural University, Hisar, 125004, India

    Anil Panghal

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  1. Poorva Sharma
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Correspondence to Anil Panghal.

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Sharma, P., Kaur, H., Kehinde, B.A. et al. Food-Derived Anticancer Peptides: A Review. Int J Pept Res Ther 27, 55–70 (2021). https://doi.org/10.1007/s10989-020-10063-1

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