Purpose

The state of Veracruz, Mexico, is a well-recognized endemic region for Chagas disease, but congenital transmission has not been extensively studied. We estimated here the prevalence and the risk of congenital transmission of Trypanosoma cruzi in pregnant women from 27 municipalities of central Veracruz.

Methods

528 sera from pregnant women were analyzed by ELISA and IFA assays for the detection of IgG antibodies against T. cruzi.

Results

The presence of anti-T. cruzi antibodies was identified in women from 17 municipalities, obtaining an overall seroprevalence of 17.0%. A higher seropositivity was observed in the municipalities of Orizaba (25.2%), Nogales (13.6%), and Río Blanco (10.5%). The results suggest that there is a high risk of congenital transmission of T. cruzi in the region.

Conclusion

There are currently limited actions for the surveillance and control of congenital transmission of Chagas disease in Veracruz.

中文翻译：

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孕妇克鲁氏锥虫感染的血清流行率表明，墨西哥中部韦拉克鲁斯州先天性传播的风险很高。

目的

墨西哥韦拉克鲁斯州是公认的恰加斯病流行地区，但先天性传播尚未得到广泛研究。我们在这里估计了韦拉克鲁斯州中部27个城市的孕妇克鲁斯锥虫的患病率和先天性传播风险。

方法

通过ELISA和IFA分析法对孕妇528份血清进行了检测，以检测抗曲霉的IgG抗体。

结果

在来自17个市镇的女性中鉴定出存在抗T. cruzi抗体，总体血清阳性率为17.0％。在Orizaba（25.2％），Nogales（13.6％）和RíoBlanco（10.5％）的市镇中，观察到较高的血清阳性。结果表明该地区存在先天性传播克氏锥虫的风险。

结论

目前在韦拉克鲁斯州监测和控制南美锥虫病先天性传播的行动有限。