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Food Allergy Insights: A Changing Landscape.
Archivum Immunologiae et Therapiae Experimentalis ( IF 2.9 ) Pub Date : 2020-04-01 , DOI: 10.1007/s00005-020-00574-6
Massimo De Martinis 1, 2 , Maria Maddalena Sirufo 1, 2 , Angelo Viscido 3 , Lia Ginaldi 1, 2
Affiliation  

The panorama of food allergies (FA) has changed profoundly in recent years. In light of recent advances in knowledge of pathogenetic mechanisms and a greater attention to the multifaceted range of possible clinical manifestations, there is a need for a critical review of past classifications. Changes in nutrition, environment and lifestyles around the world are modifying the global FA epidemiology and new FA phenotypes are also emerging. Furthermore, both biotechnological advances in this field and recent personalized therapies have improved the diagnostic and therapeutic approach to FA. Consequently, both the prevention and clinical management of FA are rapidly changing and new therapeutic strategies are emerging, even revolutionizing the current medical practice. Given the significant increase in the prevalence of FA in recent years, the objective of this review is to provide an updated and complete overview of current knowledge in its etiopathogenesis, diagnostics and therapy, useful not only for a better understanding of this frequent and complex pathology but also for practical guidance in its clinical management.

中文翻译:

食品过敏见解:不断变化的格局。

近年来,食物过敏(FA)的全景发生了深刻的变化。鉴于致病机理知识的最新进展以及对可能临床表现的多方面的关注,对过去的分类进行了严格的审查。全球营养,环境和生活方式的变化正在改变全球FA流行病学,新的FA表型也正在出现。此外,该领域的生物技术进步和最近的个性化疗法都改善了FA的诊断和治疗方法。因此,FA的预防和临床管理都在迅速变化,并且出现了新的治疗策略,甚至改变了当前的医学实践。鉴于近年来FA的患病率显着上升,
更新日期:2020-04-20
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