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Evaluation of the susceptibility test of polymyxin B using the commercial test Policimbac®
Brazilian Journal of Microbiology ( IF 2.1 ) Pub Date : 2020-03-20 , DOI: 10.1007/s42770-020-00246-9
Tanise Vendruscolo Dalmolin 1, 2 , Maiara Dos Santos Carneiro 1, 2 , Luíza Peres de Castro 1 , Fabiana Caroline Zempulski Volpato 1, 3 , Priscila Lamb Wink 1, 2 , Daiana de Lima-Morales 1 , Afonso Luís Barth 1, 2, 3
Affiliation  

Broth microdilution (BMD), the reference method to determine bacterial susceptibility to polymyxins, is a laborious and time-consuming technique. Policimbac® is a commercial test panel which uses lyophilized polymyxin B to determine the minimum inhibitory concentration for Gram-negative isolates. This study evaluated the performance of Policimbac® in comparison with BMD for 110 isolates. Although the Policimbac® presented a very low essential agreement, the categorical agreement with BMD was optimal. Policimbac® is an alternative approach to BMD for evaluating the susceptibility to polymyxin B.

中文翻译:

使用商业测试 Policimbac® 评估多粘菌素 B 的敏感性测试

肉汤微量稀释 (BMD) 是确定细菌对多粘菌素敏感性的参考方法,是一项费时费力的技术。Policimbac® 是一种商业测试板,它使用冻干的多粘菌素 B 来确定革兰氏阴性分离株的最低抑菌浓度。本研究评估了 Policimbac® 与 110 个分离株的 BMD 相比的性能。尽管 Policimbac® 的基本一致性非常低,但与 BMD 的分类一致性是最佳的。Policimbac® 是 BMD 的替代方法,用于评估对多粘菌素 B 的敏感性。
更新日期:2020-03-20
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