Abstract
Broth microdilution (BMD), the reference method to determine bacterial susceptibility to polymyxins, is a laborious and time-consuming technique. Policimbac® is a commercial test panel which uses lyophilized polymyxin B to determine the minimum inhibitory concentration for Gram-negative isolates. This study evaluated the performance of Policimbac® in comparison with BMD for 110 isolates. Although the Policimbac® presented a very low essential agreement, the categorical agreement with BMD was optimal. Policimbac® is an alternative approach to BMD for evaluating the susceptibility to polymyxin B.
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Funding
This work was supported in part by Fundo de Incentivo a Pesquisa e Eventos do Hospital de Clínicas de Porto Alegre (FIPE/HCPA) (project no. 16-0559).
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Dalmolin, T.V., Carneiro, M.d., de Castro, L.P. et al. Evaluation of the susceptibility test of polymyxin B using the commercial test Policimbac®. Braz J Microbiol 51, 1135–1137 (2020). https://doi.org/10.1007/s42770-020-00246-9
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DOI: https://doi.org/10.1007/s42770-020-00246-9