Improving the strength of bone cement is one of the critical goals in cement designing to maintain their integrity and stabilize connection between the cement and their surrounding tissue during the time that the cement has been replaced by matured bone tissue. To this aim, the authors decided to evaluate setting behavior and compressive strength of Magnesium Phosphate Cement (MPC) by adding car-boxylated Single-Walled Carbon Nanotubes (c-SWCNTs) and assess the biocompatibility of the composite cement. MPC containing 0 wt% to 0.5 wt% of c-SWCNTs at the Powder to Liquid Ratio (PLR) of 1 g-mL^-1 to 2 g-mL^-1 were produced. Adding c-SWCNTs to MPC postponed the setting time of the cement at the beginning of the cementation process and preserved the reaction with a high rate for a longer time. In addition, the compressive strength of MPC was enhanced to 28 MPa by adding 0.2 wt% c-SWCNTs because of producing cement with compact and uniform micro structure. In addition, cell behavior on MPC with/without c-SWCNTs indicated no cytotoxic effect alongside a suitable adhesion and proliferation of them.

中文翻译：

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Mg-P / c-SWCNT骨水泥：填料对凝固行为，抗压强度和生物相容性的影响

提高骨水泥的强度是骨水泥设计中的关键目标之一，在骨水泥被成熟的骨组织替代后，保持骨水泥的完整性并稳定骨水泥与周围组织之间的连接。为此，作者决定通过添加羧基化的单壁碳纳米管（c-SWCNT）来评估磷酸镁水泥（MPC）的凝结行为和抗压强度，并评估复合水泥的生物相容性。MPC含有1 wt-0.5 wt％至0.5 wt％的c-SWCNT，粉液比（PLR）为1 g-mL ^-1至2 g-mL ^-1被生产了。在MPC中添加c-SWCNTs会延迟水泥在胶结过程开始时的凝固时间，并在较长时间内保持较高的反应速率。另外，由于产生具有致密且均匀的微观结构的水泥，通过添加0.2重量％的c-SWCNT将MPC的压缩强度提高至28MPa。另外，具有/不具有c-SWCNT的MPC上的细胞行为表明，除了它们的适当粘附和增殖外，没有细胞毒性作用。