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Mg-P/c-SWCNT Bone Cement: The Effect of Filler on Setting Behavior, Compressive Strength and Biocompatibility

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Abstract

Improving the strength of bone cement is one of the critical goals in cement designing to maintain their integrity and stabilize connection between the cement and their surrounding tissue during the time that the cement has been replaced by matured bone tissue. To this aim, the authors decided to evaluate setting behavior and compressive strength of Magnesium Phosphate Cement (MPC) by adding car-boxylated Single-Walled Carbon Nanotubes (c-SWCNTs) and assess the biocompatibility of the composite cement. MPC containing 0 wt% to 0.5 wt% of c-SWCNTs at the Powder to Liquid Ratio (PLR) of 1 g-mL-1 to 2 g-mL-1 were produced. Adding c-SWCNTs to MPC postponed the setting time of the cement at the beginning of the cementation process and preserved the reaction with a high rate for a longer time. In addition, the compressive strength of MPC was enhanced to 28 MPa by adding 0.2 wt% c-SWCNTs because of producing cement with compact and uniform micro structure. In addition, cell behavior on MPC with/without c-SWCNTs indicated no cytotoxic effect alongside a suitable adhesion and proliferation of them.

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Authors and Affiliations

  1. School of Metallurgical and Materials Engineering, Iran University of Science and Technology, Narmak, Tehran, 16844, Iran

    Mohammad Hossein Esnaashary, Alireza Khavandi, Hamid Reza Rezaie & Jafar Javadpour

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  1. Mohammad Hossein Esnaashary
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  2. Alireza Khavandi
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  3. Hamid Reza Rezaie
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  4. Jafar Javadpour
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Correspondence to Mohammad Hossein Esnaashary.

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Esnaashary, M.H., Khavandi, A., Rezaie, H.R. et al. Mg-P/c-SWCNT Bone Cement: The Effect of Filler on Setting Behavior, Compressive Strength and Biocompatibility. J Bionic Eng 17, 100–112 (2020). https://doi.org/10.1007/s42235-020-0008-5

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