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A nano-based thermotherapy for cancer stem cell-targeted therapy.
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2020-05-14 , DOI: 10.1039/d0tb00311e Xiaomin Suo 1 , Juncai Zhang 1 , Yue Zhang 1 , Xing-Jie Liang 2 , Jinchao Zhang 1 , Dandan Liu 1
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2020-05-14 , DOI: 10.1039/d0tb00311e Xiaomin Suo 1 , Juncai Zhang 1 , Yue Zhang 1 , Xing-Jie Liang 2 , Jinchao Zhang 1 , Dandan Liu 1
Affiliation
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Cancer stem cells (CSCs) exhibit high resistance to conventional therapy and are responsible for cancer metastasis and tumor relapse. Therefore, it is of significance to develop effective novel strategies to target CSCs for cancer therapies. The challenges associated with developing novel strategies include specific CSC targeting and overcoming their therapeutic resistance. In the present review, we summarize the various strategies for CSC-targeted cancer thermotherapy and combinational therapy, and the potential challenges and prospects for future work in this emerging field.
中文翻译：
基于纳米的热疗法，用于癌症干细胞靶向疗法。
癌症干细胞（CSC）对常规疗法表现出高度抵抗力，并导致癌症转移和肿瘤复发。因此，开发有效的新型策略以靶向CSCs进行癌症治疗具有重要意义。与开发新策略相关的挑战包括特定的CSC靶向和克服其治疗耐药性。在本综述中，我们总结了针对CSC的癌症热疗法和联合疗法的各种策略，以及在这个新兴领域中未来工作的潜在挑战和前景。
更新日期：2020-03-20
中文翻译：
基于纳米的热疗法，用于癌症干细胞靶向疗法。
癌症干细胞（CSC）对常规疗法表现出高度抵抗力，并导致癌症转移和肿瘤复发。因此，开发有效的新型策略以靶向CSCs进行癌症治疗具有重要意义。与开发新策略相关的挑战包括特定的CSC靶向和克服其治疗耐药性。在本综述中，我们总结了针对CSC的癌症热疗法和联合疗法的各种策略，以及在这个新兴领域中未来工作的潜在挑战和前景。
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