Issue 18, 2020
From the journal:

Journal of Materials Chemistry B

A nano-based thermotherapy for cancer stem cell-targeted therapy

Xiaomin Suo,ab   Juncai Zhang,ab   Yue Zhang,ab   Xing-Jie Liang, ORCID logo c   Jinchao Zhang ORCID logo *ab  and  Dandan Liu ORCID logo *ab  

* Corresponding authors

a Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, People's Republic of China
E-mail: leo-liudan@163.com, jczhang6970@163.com

b College of Chemistry and Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, People's Republic of China

c CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, People's Republic of China

Abstract

Cancer stem cells (CSCs) exhibit high resistance to conventional therapy and are responsible for cancer metastasis and tumor relapse. Therefore, it is of significance to develop effective novel strategies to target CSCs for cancer therapies. The challenges associated with developing novel strategies include specific CSC targeting and overcoming their therapeutic resistance. In the present review, we summarize the various strategies for CSC-targeted cancer thermotherapy and combinational therapy, and the potential challenges and prospects for future work in this emerging field.

Graphical abstract: A nano-based thermotherapy for cancer stem cell-targeted therapy

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Article information

DOI
https://doi.org/10.1039/D0TB00311E
Article type
Review Article
Submitted
05 Feb 2020
Accepted
17 Mar 2020
First published
20 Mar 2020

J. Mater. Chem. B, 2020,8, 3985-4001

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A nano-based thermotherapy for cancer stem cell-targeted therapy

X. Suo, J. Zhang, Y. Zhang, X. Liang, J. Zhang and D. Liu, J. Mater. Chem. B, 2020, 8, 3985 DOI: 10.1039/D0TB00311E

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