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Gram scale synthesis of QD 450 core–shell quantum dots for cellular imaging and sorting
Applied Nanoscience Pub Date : 2020-01-31 , DOI: 10.1007/s13204-020-01261-w
Satyanarayana Swamy Vyshnava , Gayathri Pandluru , Dileep Kumar Kanderi , Shiva Prasad Panjala , Swathi Banapuram , Kameshpandian Paramasivam , Roja Rani Anupalli , Rajashekar Reddy Bontha , Muralidhara Rao Dowlatabad

In this study, we described an easy and one-pot synthesis technique for high-quality CdZnS/ZnS core/shell quantum dots, which exhibit greater fluorescence at λ450 nm with steady quantum yields in both organic and aqueous solvents. At lower concentrations, they showed a decrease in cytotoxicity, which is more suitable for the biocompatible applications. Further, we successfully demonstrated the fluorescence imaging and sorting through the surface display of the quantum dots in MCF-7 and HELA cell lines using confocal microscopy and flow cytometer studies.

中文翻译:

用于细胞成像和分选的QD 450核-壳量子点的克级合成

在这项研究中,我们描述一个简单的和一锅合成技术为高质量CdZnS / ZnS核/壳量子点,其在λ呈现更大的荧光450与在有机和水溶剂稳定的量子产率纳米。在较低的浓度下,它们显示出细胞毒性的降低,这更适合于生物相容性应用。此外,我们使用共聚焦显微镜和流式细胞仪研究成功地证明了MCF-7和HELA细胞系中量子点表面显示的荧光成像和分类。
更新日期:2020-01-31
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