Abstract Herein, S, N doped carbon quantum dots (S, N- CQDs) were prepared by a simple hydrothermal method and characterized by transmission electron microscopy (TEM), Energy-dispersive X-ray spectroscopy (EDS) and Fourier transform infrared (FTIR) analysis. The influence of as-prepared CQDs was studied on the luminol- Mn(IV) CL reaction. The results indicated that S,N-CQDs remarkably increase the CL intensity of this reaction (about 13 fold). Furthermore, it was found that the CL intensity of S,N-CQDs–luminol-Mn(IV) system was significantly declined by uric acid. We exploited the amplified CL system to design a novel probe for the detection of uric acid. The CL intensity of S,N-CQDs–luminol-Mn(IV) reaction was proportional to the logarithm of uric acid concentration in the range of 0.05 to 1.5 µM, with a limit of detection of 17 nM. Based on these results, a sensitive and straightforward CL method was developed for the analysis of uric acid in biological fluids with satisfactory results.

中文翻译：

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S、N 掺杂的碳量子点增强 Luminol-Mn(IV) 化学发光反应，用于检测生物体液中的尿酸

摘要 本文采用简单的水热法制备了 S, N 掺杂的碳量子点 (S, N-CQDs)，并通过透射电子显微镜 (TEM)、能量色散 X 射线光谱 (EDS) 和傅里叶变换红外光谱 (FTIR) 对其进行了表征。 ） 分析。研究了制备的 CQD 对鲁米诺-Mn(IV) CL 反应的影响。结果表明，S,N-CQDs 显着增加了该反应的 CL 强度（约 13 倍）。此外，发现 S,N-CQDs-luminol-Mn(IV) 系统的 CL 强度因尿酸而显着降低。我们利用放大的 CL 系统设计了一种用于检测尿酸的新型探针。S,N-CQDs-luminol-Mn(IV) 反应的 CL 强度在 0.05 至 1.5 µM 范围内与尿酸浓度的对数成正比，检测限为 17 nM。