Distal regulatory elements control gene expression during differentiation. In this issue of Molecular Cell, Barnett et al. (2020) develop a new technology, called ATAC-Me, and discover that removal of DNA methylation is not a pre-requisite for the creation of accessible chromatin at active gene regulatory elements during cellular differentiation.

中文翻译：

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ATAC 分化过程中的 DNA 甲基化。

远端调节元件控制分化过程中的基因表达。在本期《分子细胞》中，Barnett 等人。 (2020) 开发了一种名为 ATAC-Me 的新技术，并发现去除 DNA 甲基化并不是细胞分化过程中在活性基因调控元件处创建可及染色质的先决条件。