Transdermal delivery offers several advantages in drug distribution, including convenience, painless administration, avoidance of first-pass metabolism, and ease of termination. However, the natural protective barriers of the skin, such as the stratum corneum, the topmost layer of skin, limit the systemic absorption of external therapeutics via transdermal delivery. Therefore, extensive application of transdermal delivery in medical treatment has been limited. Over the past few years, many formulation strategies and physical technologies, therefore, have been developed to enhance transdermal delivery. This review summarizes various formulation strategies proposed for transdermal delivery and their application in medical treatment.

透皮递送在药物分配中提供了多个优点，包括便利，无痛给药，避免首过代谢和易于终止。然而，皮肤的天然保护屏障，例如皮肤最表层的角质层，限制了通过透皮递送对外部治疗剂的全身吸收。因此，已经限制了透皮递送在医学中的广泛应用。因此，在过去几年中，已经开发出许多配制策略和物理技术来增强透皮递送。这篇综述总结了建议用于透皮递送的各种制剂策略及其在医学中的应用。