Purpose

This study aimed to investigate the level of fertility related quality of life (FertiQoL) in women with recurrent pregnancy loss (RPL), and to further examine moderated mediation effects of dispositional mindfulness and negative emotions on the relationship between perceived stress and FertiQoL.

Methods

A cross-sectional study was conducted with 262 participants recruited from the infertility outpatient clinics. A self-administered, structured questionnaire including the Simplified Chinese version of FertiQoL tool, the Perceived Stress Scale-10 (PSS-10), the Chinese Version of the Hospital Anxiety and Depression Scale (HADS), and the Mindfulness Attention Awareness Scale (MAAS) was used to collect information in this research. The mediation model and moderated mediation model were conducted using the PROCESS macro for SPSS.

Results

The mean score of Core FertiQoL was 64.59 (SD = 14.76) among women with RPL. Mediation analysis revealed that the association between perceived stress and FertiQoL was partially mediated by negative emotions (indirect effect = − 0.194 for anxiety, and − 0.151 for depression, all P < 0.001). Moderated mediation analysis indicated that the indirect effects of perceived stress on FertiQoL through negative emotions were significantly moderated by dispositional mindfulness. Specifically, the indirect effects of perceived stress on FertiQoL through negative emotions decreased were significant as dispositional mindfulness levels increased.

Conclusion

Overall, women with RPL experienced poor FertiQoL. The Moderated mediation model provides a better understanding of how perceived stress, negative emotions and dispositional mindfulness work together to affect FertiQoL. Interventions aiming to improve FertiQoL in women with RPL should consider targeting these aspects.

中文翻译：

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对反复流产的孕妇的生活质量进行感知压力，负面情绪和正念调适的中介模型。

目的

这项研究旨在调查复发性流产（RPL）妇女中与生育力有关的生活质量（FertiQoL）的水平，并进一步研究性取向正念和负面情绪对知觉压力与FertiQoL之间关系的调节作用。

方法

进行了一项横断面研究，从不育症门诊招募了262名参与者。一份自我管理的结构化问卷，包括简体中文版的FertiQoL工具，感知压力量表10（PSS-10），医院焦虑和抑郁量表的中文版以及正念注意意识量表（MAAS） ）用于收集这项研究中的信息。使用SPSS的PROCESS宏进行调解模型和仲裁调解模型。

结果

患有RPL的女性的Core FertiQoL平均得分为64.59（SD = 14.76）。中介分析显示，感知压力与FertiQoL之间的关联部分由负面情绪介导（间接影响=-0.194（焦虑）和-0.151（抑郁），所有P  <0.001）。主持人进行的中介分析表明，性格上的正念可以明显缓解压力通过负面情绪对FertiQoL的间接影响。具体地说，随着性格注意水平的提高，通过负面情绪而降低的感知压力对FertiQoL的间接影响是显着的。

结论

总体而言，患有RPL的女性的FertiQoL较差。主持人调解模型可以更好地理解感知的压力，负面情绪和性格正念如何共同影响FertiQoL。旨在改善RPL妇女的FertiQoL的干预措施应考虑针对这些方面。