Recent studies have shown that inflammatory diseases are becoming more frequent throughout the world. The causes of these disorders are multifactorial and include genetic, immunological, and environmental factors, and intestinal microbiota dysbiosis. The use of beneficial microorganisms has shown to be useful in the prevention and treatment of disorders such as colitis, mucositis, and even colon cancer by their immune-stimulating properties. It has also been shown that certain vitamins, especially riboflavin and folate derivatives, have proven to be helpful in the treatment of these diseases. The application of vitamin-producing lactic acid bacteria, especially strains that produce folate and riboflavin together with immune-stimulating strains, could be used as adjunct treatments in patients suffering from a wide range of inflammatory diseases since they could improve treatment efficiency and prevent undesirable side effects in addition to their nutrition values. In this review, the most up to date information on the current knowledge and uses of vitamin-producing lactic acid bacteria is discussed in order to stimulate further studies in this field.

中文翻译：

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产生维生素的乳酸菌在治疗肠道炎性疾病中的应用。

最近的研究表明，炎症性疾病在世界范围内越来越普遍。这些疾病的原因是多因素的，包括遗传，免疫和环境因素，以及肠道菌群失调。有益微生物的使用已显示出通过其免疫刺激特性可用于预防和治疗疾病，例如结肠炎，粘膜炎，甚至结肠癌。还已经表明，某些维生素，特别是核黄素和叶酸衍生物，已被证明有助于治疗这些疾病。产生维生素的乳酸菌的应用，特别是产生叶酸和核黄素的菌株以及刺激免疫的菌株，由于它们可以提高治疗效率并防止营养不良，因此可以用作治疗多种炎症性疾病的辅助治疗。在这篇综述中，讨论了有关生产维生素的乳酸菌的当前知识和用途的最新信息，以促进该领域的进一步研究。