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Pharmacologic labour analgesia and its relationship to postpartum psychiatric disorders: a scoping review.
Canadian Journal of Anesthesia ( IF 3.4 ) Pub Date : 2020-02-04 , DOI: 10.1007/s12630-020-01587-7
Allana Munro 1, 2 , Hilary MacCormick 1, 2 , Atul Sabharwal 3 , Ronald B George 4
Affiliation  

PURPOSE This scoping review aimed to summarize the current literature on postpartum psychiatric disorders (e.g., postpartum depression, postpartum anxiety, postpartum post-traumatic stress disorder) and the possible relationship of these disorders to the use of pharmacologic labour analgesia (e.g., epidural analgesia, nitrous oxide, parenteral opioids) to identify knowledge gaps that may aid in the planning of future research. SOURCES PubMed, PsycINFO, CINAHL, and EMBASE were searched from inception to November 9, 2018 for studies that included both labour analgesia and the postpartum psychiatric disorders specified above. PRINCIPAL FINDINGS Two reviewers assessed the studies and extracted the data. Of the 990 identified citations, 17 studies were included for analysis. Existing studies have small sample sizes and are observational cohorts in design. Patient psychiatric risk factors, method of delivery, and type of labour analgesia received were inconsistent among studies. Most studies relied on screening tests for diagnosing postpartum psychiatric illness and did not assess the impact of labour analgesia on postpartum psychiatric illness as the primary study objective. CONCLUSIONS Future studies should correlate screen-positive findings with clinical diagnosis; consider adjusting the timing of screening to include the antepartum period, early postpartum, and late postpartum periods; and consider the degree of labour pain relief and the specific pharmacologic labour analgesia used when evaluating postpartum psychiatric disorders.

中文翻译:

药理学分娩镇痛及其与产后精神疾病的关系:范围审查。

目的 本综述旨在总结当前关于产后精神疾病(例如,产后抑郁症、产后焦虑症、产后创伤后应激障碍)的文献,以及这些疾病与使用药物分娩镇痛药(例如,硬膜外镇痛、一氧化二氮,肠胃外阿片类药物),以确定可能有助于规划未来研究的知识差距。资料来源 PubMed、PsycINFO、CINAHL 和 EMBASE 从开始到 2018 年 11 月 9 日进行了搜索,以查找包括分娩镇痛和上述产后精神疾病的研究。主要发现 两名审查员评估了研究并提取了数据。在 990 条已确定的引文中,有 17 项研究被纳入分析。现有研究的样本量较小,并且在设计上是观察性队列。研究中的患者精神危险因素、分娩方法和分娩镇痛剂类型不一致。大多数研究依赖于诊断产后精神疾病的筛查测试,并未将分娩镇痛对产后精神疾病的影响作为主要研究目标。结论 未来的研究应将筛查阳性结果与临床诊断联系起来;考虑调整筛查时间,包括产前、产后早期和产后晚期;并考虑分娩疼痛缓解的程度和评估产后精神疾病时使用的特定药物分娩镇痛。研究中接受的分娩镇痛剂类型和类型不一致。大多数研究依赖于诊断产后精神疾病的筛查测试,并未将分娩镇痛对产后精神疾病的影响作为主要研究目标。结论 未来的研究应将筛查阳性结果与临床诊断联系起来;考虑调整筛查时间,包括产前、产后早期和产后晚期;并考虑分娩疼痛缓解的程度和评估产后精神疾病时使用的特定药物分娩镇痛。研究中接受的分娩镇痛剂类型和类型不一致。大多数研究依赖于诊断产后精神疾病的筛查测试,并未将分娩镇痛对产后精神疾病的影响作为主要研究目标。结论 未来的研究应将筛查阳性结果与临床诊断联系起来;考虑调整筛查时间,包括产前、产后早期和产后晚期;并考虑分娩疼痛缓解的程度和评估产后精神疾病时使用的特定药物分娩镇痛。大多数研究依赖于诊断产后精神疾病的筛查测试,并未将分娩镇痛对产后精神疾病的影响作为主要研究目标。结论 未来的研究应将筛查阳性结果与临床诊断联系起来;考虑调整筛查时间,包括产前、产后早期和产后晚期;并考虑分娩疼痛缓解的程度和评估产后精神疾病时使用的特定药物分娩镇痛。大多数研究依赖于诊断产后精神疾病的筛查测试,并未将分娩镇痛对产后精神疾病的影响作为主要研究目标。结论 未来的研究应将筛查阳性结果与临床诊断联系起来;考虑调整筛查时间,包括产前、产后早期和产后晚期;并考虑分娩疼痛缓解的程度和评估产后精神疾病时使用的特定药物分娩镇痛。
更新日期:2020-04-20
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