To integrate auditory and visual signals into a unified percept, the paired stimuli must co-occur within a limited time window known as the Temporal Binding Window (TBW). The width of the TBW, a proxy of audiovisual temporal integration ability, has been found to be correlated with higher-order cognitive and social functions. A comprehensive review of studies investigating audiovisual TBW reveals several findings: (1) a wide range of top-down processes and bottom-up features can modulate the width of the TBW, facilitating adaptation to the changing and multisensory external environment; (2) a large-scale brain network works in coordination to ensure successful detection of audiovisual (a)synchrony; (3) developmentally, audiovisual TBW follows a U-shaped pattern across the lifespan, with a protracted developmental course into late adolescence and rebounding in size again in late life; (4) an enlarged TBW is characteristic of a number of neurodevelopmental disorders; and (5) the TBW is highly flexible via perceptual and musical training. Interventions targeting the TBW may be able to improve multisensory function and ameliorate social communicative symptoms in clinical populations.

中文翻译：

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视听时间整合：认知过程，神经机制，发展轨迹和潜在干预措施。

要将听觉和视觉信号整合到一个统一的感知中，必须在称为时间绑定窗口（TBW）的有限时间窗口内同时出现配对的刺激。已经发现，TBW的宽度是视听时间整合能力的代表，与更高阶的认知和社会功能相关。对研究视听TBW的研究的全面回顾揭示了以下发现：（1）多种自上而下的过程和自下而上的功能可以调节TBW的宽度，从而有助于适应不断变化的多感官外部环境；（2）大规模的大脑网络协同工作，以确保成功检测到视听（a）同步；（3）从发展上看，视听TBW在整个生命周期中呈U形模式，进入青春期的漫长的发展过程，以及后期的体型再次反弹；（4）TBW增大是许多神经发育障碍的特征；（5）TBW通过感知和音乐训练具有很高的灵活性。针对TBW的干预措施可能能够改善临床人群的多感官功能并改善社交交际症状。