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CD36 — the Achilles’ heel of T reg cells
Nature Immunology ( IF 27.7 ) Pub Date : 2020-02-17 , DOI: 10.1038/s41590-020-0601-0
Brendan L. Horton , Stefani Spranger

Regulatory T (Treg) cells suppress antitumor immunity, but Treg cell inhibition has been hampered by a lack of specific targets. CD36 expression by tumor-infiltrating Treg cells may provide a way to specifically target Treg cells in tumors.

中文翻译:

CD36 — T reg细胞的致命弱点

调节性T(Treg)细胞可抑制抗肿瘤免疫力,但由于缺乏特异性靶标,Treg细胞的抑制作用受到阻碍。肿瘤浸润的Treg细胞表达CD36可能提供一种特异性靶向肿瘤中Treg细胞的方法。
更新日期:2020-02-17
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