In this review article the available results about application of sol–gel synthesis method for the preparation of different calcium phosphates and composite materials are summarized. The attention is paid to calcium phosphate-containing compounds which show the biological properties and could be used as potential phosphate bioceramics in medicine. It was demonstrated that the sol–gel synthesis method is a powerful tool for the synthesis of calcium hydroxyapatite and other phosphates, and different calcium phosphate-based composites at mild synthetic conditions resulted in high reproducibility, high phase purity, and desired morphology. Thus, the sol–gel synthesis method enables the researchers to develop biomaterials with superior features in terms of biomedical applications.

For the synthesis of calcium phosphate biomaterials an effective sol–gel chemistry approaches have been developed. KI, EG, and AK. “Sol–gel synthesis of calcium phosphate-based biomaterials—A review of environmentally benign, simple, and effective synthesis routes”.

在这篇综述文章中，总结了关于溶胶-凝胶合成方法在制备不同的磷酸钙和复合材料中的应用可获得的结果。注意力集中在具有磷酸钙的化合物上，这些化合物具有生物学特性，可以在医学中用作潜在的磷酸盐生物陶瓷。结果表明，溶胶-凝胶合成方法是合成羟基磷灰石钙和其他磷酸盐的有力工具，在温和的合成条件下，不同的磷酸钙基复合材料可实现高重现性，高相纯度和所需的形态。因此，溶胶-凝胶合成方法使研究人员能够开发在生物医学应用方面具有卓越功能的生物材料。

为了合成磷酸钙生物材料，已经开发了一种有效的溶胶-凝胶化学方法。KI，EG和AK。“磷酸钙基生物材料的溶胶-凝胶合成-对环境友好，简单而有效的合成途径的综述”。